Pearson Edexcel International GCSE in Biology · 4BI1 · Free · no account needed

Pedigrees and Sex Determination — exam questions

10 original Incandio exam-style questions on Pedigrees and Sex Determination, 24 marks, about 24 minutes of writing. Each one carries the command word, the tariff and the specification statement it assesses, exactly as a paper presents them. This is an original Incandio practice question, written to reflect the structure and demands of the qualification. It is not an official Pearson Edexcel past-paper question.

This is the practice set for Pedigrees and Sex Determination — the lesson that teaches it. Read the lesson first if the idea is new; come here when you want to find out whether you can turn it into marks. Completely free, no account needed to read.

What these questions ask of you

8 command words run through this set, and on Pearson Edexcel International GCSE Biology each one means something precise. Answering the wrong command is the commonest way a candidate who understands the lesson still loses the mark.

Which (1 mark)
one option chosen from the set given
State (1 mark)
one precise fact, no justification
Complete (1–5 marks)
the missing entries in a table, diagram or sentence
Explain (2–4 marks)
a causal chain — WHY it happens, each link a separate marking point Misread as: describing what happens without giving the reason it happens
Describe (2–4 marks)
developed, linked statements of WHAT happens — no reason required, but detail is Misread as: giving one bare statement where the tariff asked for a developed account
Suggest (1–3 marks)
a plausible answer applying taught biology to a situation not taught
Give (1–2 marks)
a short factual answer drawn from recall or from the data
Use (2–5 marks)
the supplied data, graph or diagram applied to reach a result — the data is not optional

Assessed on Paper 1 (4BI1/1B) and Paper 2 (4BI1/2B), against AO1, AO2, AO3.

Where these sit in the specification

Pearson Edexcel International GCSE Biology (4BI1) — statements 3.26 · 3.27 · 3.24. Incandio is aligned to this specification; it is not published by, endorsed by or affiliated with Pearson, and it reproduces none of Pearson's wording.

The 10 questions

Answer them on paper, then open the lesson's exam practice to have them marked. The mark scheme, the accepted and rejected answers and the annotated model answer are in Incandio and are not printed here — an answer beside its question is not practice.

  1. Table 1 — a family in which some members have an inherited condition. Individuals 1 and 2 are the parents of individuals 3, 4 and 5.
    IndividualSexHas the condition?
    1maleno
    2femaleno
    3femaleyes
    4maleno
    5maleno

    (a)

    (1)Give

    Give the individual in Table 1 who shows that the allele causing the condition is recessive.

    Table 1 — a family in which some members have an inherited condition. Individuals 1 and 2 are the parents of individuals 3, 4 and 5.
    IndividualSexHas the condition?
    1maleno
    2femaleno
    3femaleyes
    4maleno
    5maleno

    individual = ............................

    Specification 3.24 · AO3 · about 1 min

    (b)

    (3)Explain

    Explain how the genotypes of individuals 1 and 2 can be worked out from Table 1.

    Table 1 — a family in which some members have an inherited condition. Individuals 1 and 2 are the parents of individuals 3, 4 and 5.
    IndividualSexHas the condition?
    1maleno
    2femaleno
    3femaleyes
    4maleno
    5maleno

    Specification 3.24 · AO2 + AO3 · about 3 min

    (c)

    (2)Suggest

    Suggest what can and cannot be said about the genotype of individual 4.

    Table 1 — a family in which some members have an inherited condition. Individuals 1 and 2 are the parents of individuals 3, 4 and 5.
    IndividualSexHas the condition?
    1maleno
    2femaleno
    3femaleyes
    4maleno
    5maleno

    Specification 3.24 · AO2 + AO3 · about 2 min

    (Total for Question 1 = 6 marks)

  2. (1)Which

    Which pair of sex chromosomes does a human male carry?

    Chromosomes
    AXX
    BXY
    CYY
    DXO

    Specification 3.26 · AO1 · about 1 min

    (Total for Question 2 = 1 mark)

  3. (1)State

    State which parent determines the sex of a child.

    Specification 3.26 · AO1 · about 1 min

    (Total for Question 3 = 1 mark)

  4. (3)Complete

    Complete a genetic diagram to show how the sex of a child is determined, giving the parents' chromosomes, their gametes and the possible offspring.

    A Punnett square for a heterozygous cross giving a 3 to 1 ratio
    Figure 2 — a genetic diagram for a cross between two heterozygous parents.

    Specification 3.27 · AO1 + AO2 · about 3 min

    (Total for Question 4 = 3 marks)

  5. (2)Explain

    A couple have four sons. Explain why their chance of having a daughter next time is still one half.

    Specification 3.27 · AO2 · about 2 min

    (Total for Question 5 = 2 marks)

  6. (3)Describe

    Describe how to work out from a family pedigree whether an allele is dominant or recessive.

    A family pedigree showing an unaffected couple with an affected child
    Figure 1 — a family pedigree. Shaded symbols show individuals with the condition.

    Specification 3.24 · AO1 + AO2 · about 3 min

    (Total for Question 6 = 3 marks)

  7. (3)Suggest

    In some reptiles the sex of the offspring is determined by the temperature at which the eggs develop rather than by chromosomes. Suggest one disadvantage of this to the species.

    Specification 3.26 · AO2 · about 3 min

    (Total for Question 7 = 3 marks)

  8. (5)Use

    Use Table 2 to decide whether the condition is caused by a dominant or a recessive allele, and to explain how you can be certain.

    Table 2 — four families, showing whether each parent and child has the condition.
    FamilyMotherFatherChildren with the conditionChildren without
    1unaffectedunaffected13
    2unaffectedaffected04
    3affectedunaffected22
    4unaffectedunaffected05

    Specification 3.24, 3.26, 3.27 · AO1 + AO2 + AO3 · about 5 min

    (Total for Question 8 = 5 marks)

Have them marked, then defend the answer

Practice tells you the mark; teaching it back tells you whether you understand it. On Incandio a topic counts as mastered only once you have taught it and defended it.

  1. Mark these questions — 10 questions, marked on Incandio against the authored scheme, with the mistake you actually made named.
  2. Teach it — explain Pedigrees and Sex Determination to Ember, an AI pupil who does not have it yet and asks the awkward question.
  3. Defend it — argue it against Aristotle over three rounds, marked against descriptors you can read first.

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