Pearson Edexcel International GCSE in Biology · 4BI1 · Free · no account needed
Immunity and Clotting — exam questions
9 original Incandio exam-style questions on Immunity and Clotting, 21 marks, about 21 minutes of writing. Each one carries the command word, the tariff and the specification statement it assesses, exactly as a paper presents them. This is an original Incandio practice question, written to reflect the structure and demands of the qualification. It is not an official Pearson Edexcel past-paper question.
This is the practice set for Immunity and Clotting — the lesson that teaches it. Read the lesson first if the idea is new; come here when you want to find out whether you can turn it into marks. Completely free, no account needed to read.
What these questions ask of you
7 command words run through this set, and on Pearson Edexcel International GCSE Biology each one means something precise. Answering the wrong command is the commonest way a candidate who understands the lesson still loses the mark.
- Which (1 mark)
- one option chosen from the set given
- State what is meant by (1–2 marks)
- the definition
- Describe (2–4 marks)
- developed, linked statements of WHAT happens — no reason required, but detail is Misread as: giving one bare statement where the tariff asked for a developed account
- Explain (2–4 marks)
- a causal chain — WHY it happens, each link a separate marking point Misread as: describing what happens without giving the reason it happens
- Compare (2–4 marks)
- explicit points of similarity or difference, each naming BOTH things
- Suggest (1–3 marks)
- a plausible answer applying taught biology to a situation not taught
- Give (1–2 marks)
- a short factual answer drawn from recall or from the data
Assessed on Paper 1 (4BI1/1B) and Paper 2 (4BI1/2B), against AO1, AO2, AO3.
Where these sit in the specification
Pearson Edexcel International GCSE Biology (4BI1) — statements 2.62 · 2.64 · 2.63. Incandio is aligned to this specification; it is not published by, endorsed by or affiliated with Pearson, and it reproduces none of Pearson's wording.
The 9 questions
Answer them on paper, then open the lesson's exam practice to have them marked. The mark scheme, the accepted and rejected answers and the annotated model answer are in Incandio and are not printed here — an answer beside its question is not practice.
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Figure 1 — antibody concentration in the blood after a first injection of a vaccine on day 0. Plotted as a line; the graph is drawn in Incandio and the readings are below. Time / days Antibody concentration / arbitrary units 0 0 4 1 8 9 12 17 16 14 24 8 40 4 Figure 2 — antibody concentration after a booster of the same vaccine, given to the same person on day 60. Plotted as a line; the graph is drawn in Incandio and the readings are below. Time from booster / days Antibody concentration / arbitrary units 0 4 2 26 4 78 8 112 16 96 24 74 40 55 (a)
(1)Give
Give the highest antibody concentration reached in Figure 1.
Figure 1 — antibody concentration in the blood after a first injection of a vaccine on day 0. Plotted as a line; the graph is drawn in Incandio and the readings are below. Time / days Antibody concentration / arbitrary units 0 0 4 1 8 9 12 17 16 14 24 8 40 4 Figure 2 — antibody concentration after a booster of the same vaccine, given to the same person on day 60. Plotted as a line; the graph is drawn in Incandio and the readings are below. Time from booster / days Antibody concentration / arbitrary units 0 4 2 26 4 78 8 112 16 96 24 74 40 55 (b)
(2)Describe
Describe two differences between the response shown in Figure 2 and the response shown in Figure 1.
Figure 1 — antibody concentration in the blood after a first injection of a vaccine on day 0. Plotted as a line; the graph is drawn in Incandio and the readings are below. Time / days Antibody concentration / arbitrary units 0 0 4 1 8 9 12 17 16 14 24 8 40 4 Figure 2 — antibody concentration after a booster of the same vaccine, given to the same person on day 60. Plotted as a line; the graph is drawn in Incandio and the readings are below. Time from booster / days Antibody concentration / arbitrary units 0 4 2 26 4 78 8 112 16 96 24 74 40 55 (c)
(3)Explain
Explain what the difference between the two figures shows about the effect of the first injection.
Figure 1 — antibody concentration in the blood after a first injection of a vaccine on day 0. Plotted as a line; the graph is drawn in Incandio and the readings are below. Time / days Antibody concentration / arbitrary units 0 0 4 1 8 9 12 17 16 14 24 8 40 4 Figure 2 — antibody concentration after a booster of the same vaccine, given to the same person on day 60. Plotted as a line; the graph is drawn in Incandio and the readings are below. Time from booster / days Antibody concentration / arbitrary units 0 4 2 26 4 78 8 112 16 96 24 74 40 55 (Total for Question 1 = 6 marks)
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(1)Which
Which type of white blood cell engulfs and digests pathogens?
Cell A a phagocyte B a lymphocyte C a platelet D a red blood cell (Total for Question 2 = 1 mark)
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(1)State what is meant by
State what is meant by an antigen.
(Total for Question 3 = 1 mark)
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(3)Describe
Describe the part platelets play when a blood vessel is cut.
(Total for Question 4 = 3 marks)
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(4)Explain
Explain how a vaccine protects a person from a disease they have never had.
(Total for Question 5 = 4 marks)
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(3)Compare
Compare the way a phagocyte deals with a pathogen with the way a lymphocyte does.
(Total for Question 6 = 3 marks)
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(3)Suggest
Suggest why a vaccine against one strain of a virus may give no protection against a different strain of the same virus.
(Total for Question 7 = 3 marks)
Have them marked, then defend the answer
Practice tells you the mark; teaching it back tells you whether you understand it. On Incandio a topic counts as mastered only once you have taught it and defended it.
- Mark these questions — 9 questions, marked on Incandio against the authored scheme, with the mistake you actually made named.
- Teach it — explain Immunity and Clotting to Ember, an AI pupil who does not have it yet and asks the awkward question.
- Defend it — argue it against Edward Jenner over three rounds, marked against descriptors you can read first.
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Back to the lesson
- Immunity and Clotting — You are a warm, wet, nutrient-rich environment. Two kinds of white cell — and one clever trick with a scab — are why nothing has eaten you yet.
- All of Incandio Biology · Incandio Exam Practice